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What to expect — people who have been taking prednisone for a very long time may need a much slower taper. In some cases, the dose may be decreased monthly. 21 мая 2010 г. 16 сообщений · 8 авторов. Pmr can return if you stop this medicine too quickly. The usual dose of prednisone is between 10 and 20 mg per day. You may need to take corticosteroids as. After an appropriate therapeutic response has been observed, the dose of prednisone should be maintained for 2-4 weeks, after which time prednisone may be. 7 мая 2019 г. — how much alcohol the person drinks. In general, a person's doctor can best determine whether mixing prednisone with alcohol will be safe. And a good response to low doses of prednisone. Take your prednisone tablets with food and with a full glass of water. 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