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The use of cannabis, and indeed alcohol and tobacco, has increased in both sexes, and especially in males, over the past 3 decades [2]. For example, in 1981, the U.S. Department of Health and Human Services reported 1,800,000 annual admissions into US hospitals. The estimated costs of treatment for addiction to these drugs were approximately US $5.6 billion and these are on the conservative end of estimates [2]. Cannabinoids such as 1‐arachidonoylglycerol (1–AG) produced by the plant are thought to be important mediators of both effects of THC and cannabis. 1‐AG is an essential oil of the cannabis plant that has been shown to have cannabinoid‐like activities in the body. 1‐AG appears to have a neuroprotective property and was found to be more potent than the more commonly used THC in reducing the incidence of neuropathic pain and the effects of multiple sclerosis (MS) [3,4,5]. 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